What type of insulin can be given iv




















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Build your knowledge with top universities and organisations. Learn more about how FutureLearn is transforming access to education. Learn more about this course. What are the routes of administration for insulin? Helps the learner to be familiar with the means by which insulin can be provided for administration.

Insulin is only available as a liquid preparation. Want to keep learning? This content is taken from University of Southampton online course,. In the United Kingdom, only people with type 1 diabetes who meet essential criteria are entitled to a trial of insulin pump therapy. Did you know? Research with new technology i.

This system continuously checks blood glucose levels and the calculates how much insulin is required before automatically delivering the correct amount of insulin through the pump. This leads to improved glucose control. For more information, see the guidelines for continuous glucose monitoring in Diabetes UK.

If a person in hospital is unwell with uncontrolled high blood glucose levels, insulin can be administered through an intravenous insulin infusion. It is only rapid or short acting insulin that is administered by this route. The hourly rate of insulin infused is adjusted depending on the measured venous blood glucose per hour.

The aim is to keep blood glucose levels at a safe level. If the patient is not able to eat and drink, it is essential that the insulin is administered together with intravenous glucose based fluid, as the insulin needs glucose to work as a substrate to push into cells to use for energy.

This is also called subcutaneous tissue. See a table of insulin action below and a graphic illustration of onset of action , peak effect and duration of action of the different insulins. There are three main groups of insulins: Fast-acting, Intermediate-acting and Long-acting insulin.

Rapid Acting Insulin Analogs Insulin Aspart, insulin Lyspro, Insulin Glulisine which have an onset of action of 5 to 15 minutes, peak effect in 1 to 2 hours and duration of action that lasts hours. With all doses, large and small, the onset of action and the time to peak effect is similar, The duration of insulin action is, however, affected by the dose — so a few units may last 4 hours or less, while 25 or 30 units may last 5 to 6 hours.

As a general rule, assume that these insulins have duration of action of 4 hours. The larger the dose of regular the faster the onset of action, but the longer the time to peak effect and the longer the duration of the effect.

NPH Human Insulin which has an onset of insulin effect of 1 to 2 hours, a peak effect of 4 to 6 hours, and duration of action of more than 12 hours.

Very small doses will have an earlier peak effect and shorter duration of action, while higher doses will have a longer time to peak effect and prolonged duration. Pre-Mixed Insulin which is NPH pre-mixed with either regular human insulin or a rapid- acting insulin analog. The insulin action profile is a combination of the short and intermediate acting insulins.

The insulin effect plateaus over the next few hours and is followed by a relatively flat duration of action that lasts hours for insulin detemir and 24 hours for insulin glargine.

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